Understanding the Impact of High Estrogen on Melasma: Causes and Treatments

Updated on: 27th November, 2022

Melasma is a common skin condition characterised by brown or grey-brown patches on the face, typically on the cheeks, forehead, nose, or upper lip. It is believed to be caused by a combination of genetic, hormonal, and environmental factors, and the exact cause of melasma is not fully understood.

While the exact relationship between estrogen and melasma is complex and not entirely clear, it is believed that a high estrogen level increases the production of melanocyte-stimulating hormone (MSH). This hormone stimulates the pigment-producing cells or the melanocytes to produce more melanin. An overproduction of melanin can result in the formation of melasma patches. 

While the exact relationship between estrogen and melasma is complex and not entirely clear, it is believed that a high estrogen level increases the production of melanocyte-stimulating hormone (MSH). This hormone stimulates the pigment-producing cells or the melanocytes to produce more melanin. An overproduction of melanin can result in the formation of melasma patches. 

Pregnancy is a time when estrogen levels are significantly elevated to help maintain the pregnancy, and melasma, sometimes called “the mask of pregnancy,” is known to occur or worsen in some pregnant women. Hormonal contraceptives, such as birth control pills, which again contain estrogen, have also been shown to trigger or exacerbate melasma in some women.

Hormone replacement therapy (HRT), which involves using medications to replace or supplement hormones in the body, can also potentially increase estrogen levels and trigger or exacerbate melasma in some individuals.

However, not all cases of melasma are related to high estrogen levels. Melasma can also be triggered by other factors, such as sun exposure, certain medications, and genetic predisposition. It can affect individuals of any gender or age, regardless of estrogen levels.

The melasma treatment in Pune typically involves a combination of measures to reduce melanin production, protect the skin from further sun exposure, and address hormonal factors. 

If melasma is associated with hormonal factors, such as pregnancy or hormonal contraceptives, hormonal management may be considered. This may involve adjusting hormonal medications or discontinuing them under the guidance of a healthcare professional.

A melasma doctor can also prescribe topical creams or gels containing ingredients such as hydroquinone, tretinoin, corticosteroids, or azelaic acid that can be used to lighten the dark patches caused by melasma. He/She can also prescribe laser therapy, chemical peel or combination therapy according to the severity of the condition.