How Does Niacinamide Work to Reduce Melasma Symptoms?

Updated on: 15th July, 2022

Niacinamide, also known as vitamin B3, has gained popularity in recent years for its ability to improve a range of skin concerns, including melasma. But how exactly does niacinamide work to reduce melasma symptoms?

Niacinamide, or vitamin B3, is a water-soluble vitamin essential for maintaining healthy skin and can help reduce melasma symptoms. The exact mechanism by which niacinamide reduces melasma symptoms has yet to be fully understood, but several proposed theories exist.

Firstly, it can reduce the production of melanin, the pigment that gives colour to the skin, by inhibiting the transfer of melanosomes (pigment-containing bags) from melanocytes (pigment-making cells) to keratinocytes (skin cells). By reducing the amount of pigment produced and deposited in the skin, niacinamide can help lighten melasma’s appearance.

Niacinamide also has anti-inflammatory properties that can help reduce the inflammation and irritation associated with melasma. This can improve the skin’s overall appearance and reduce the skin’s sensitivity and reactivity.

Additionally, niacinamide has been shown to improve the barrier function of the skin, which can help to reduce the penetration of environmental irritants and pollutants that can trigger or worsen melasma. By strengthening the skin barrier, niacinamide can help to improve overall health and appearance.

Overall, niacinamide is a safe and effective treatment option for melasma and can be used alone or in combination with other treatments such as hydroquinone, retinoids, and chemical peels. However, it can cause allergic reactions, skin irritation, itching, redness and burning in sensitive people.